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Joseph Krause

Verified account Radical AI

@josephfkrause

Co-founder/CEO @RadicalAI // @usarmy veteran 🇺🇸
USA radical-ai.com Joined April 2010
1.3K Following 3.1K Followers 7.7K Posts

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Joseph Krause Verified account @josephfkrause
We believe we are building one of the most important companies in the world. The future relies on novel materials, and we are going to discover them to help create it.
History is defined by the materials we master. But the materials of the past cannot build the future. Radical AI is building scientific intelligence to autonomously discover and manufacture next-generation materials to solve the world's greatest challenges.
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Joseph Krause Verified account @josephfkrause
I have done something very similar and I am still building it out. I’ve supercharged myself as a founder and CEO…the agentic era is incredible.
Brian Armstrong Verified account @brian_armstrong 2d
I've changed how I work over the last few weeks.

I now have one lead agent for each area of focus, running all the time, and a chief of staff agent that oversees them. Each lead manages its own sub-agents that write code, test it, chase reviews, and coordinate with team members.

Everything I need to decide or review comes into one prioritized queue, a simple local web app. Each product review includes screenshots and a video demo of the feature. I clear the queue in batches, mostly by voice and keyboard shortcuts. The leads also bring back ideas I hadn't considered.

Working from one queue, instead of switching between dozens of chats, has cut a lot of mental overhead. The system keeps learning my preferences and distilling my judgment into a "Brian brain," so its recommendations and first drafts get better before they reach me. The goal is fewer corrections per change.

Every change still goes through the same human review and security checks. It is eliminating tasks, not human judgment.

What an exciting time to push the frontier of productivity, especially as we build the economy for agents (agentic finance). We should all keep pushing in this direction.
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Joseph Krause Verified account @josephfkrause
Good report…my favorite part is its scenario model estimating that automating non-physical work could increase output by as much as 15x in comp sci + statistics, but only 3-4x in chemistry + biology because physical experimentation remains limited.

So many get this wrong, but it has been why we’ve focused on building the most advanced research labs in the world since we started the company. We believe that without them, there is no ground truth.

www-cdn.anthropic.com/6e7c6446c0d840…
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