Anthropic

Anthropic has launched the roadshow for its proposed initial public offering: anthropic.com/news/roadshow-…

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Claude Fable 5.2 and Claude Mythos 5.2 are available now:

Memory is what allows Claude to learn from experience. In a new Engineering Blog post, we share how “dreaming” helps Claude organize what it’s learned, correct its mistakes, and find what it needs more easily the next time. anthropic.com/research/compo…

New on our Science Blog: How AI is beginning to change scientific modeling.

Scientific models help researchers explain and predict real-world systems—like how a single nerve cell fires, or what happens when neutron stars collide. Recent advances have transformed how scientists fit complex models to data. But scientists still typically write the models manually, and usually need to weigh up several competing versions, each of which might explain the data in a different way.

In a guest post, Jakob Macke, Daniel Gedon, and Stefan Wahl describe how AI is starting to help with these parts of the process. By writing, running, fitting, and revising scientific models as code, AI can explore many possible model structures, and find out which explanations the data support.

anthropic.com/research/teach…

We’re sharing how our biology research team worked with Claude to map the first 3D structure of a vault particle from bacterial life.

Vault particles are a longstanding mystery. They are barrel-shaped objects, among the largest protein structures found in our cells. They were first discovered by Leonard Rome and Nancy Kedersha in 1986, but their function remains unknown.

With Claude, we’ve found results that might bring us closer to solving that mystery.

Until now, vaults were only known in the cells of complex things like animals and plants. We have shown that similar proteins from bacteria (and the viruses that infect them) can also assemble into vaults. Finding the structures in these simpler forms of life may make it easier to investigate their function in our own cells.

For our life sciences team, the project was also a demonstration of the potential (and the limitations) of using AI to accelerate science.

In our full piece, we discuss how Claude was able to dramatically speed up some stages—manually determining the vault particle’s structure would have taken weeks to months of painstaking work, but here it took days. We also discuss how Claude made some simple mistakes along the way, and how we collaborated with our machine learning researchers to address them.

Read more: anthropic.com/research/inves…