@AOSasmita
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link.springer.com Targeting the peripheral immune system for treatment of Alzheimer’s disease Molecular Neurodegeneration Advances - Alzheimer’s disease (AD) has traditionally been viewed as a central nervous system (CNS)-restricted proteinopathy. Although this neurocentric focus has... 
link.springer.com Estrogen deprivation exacerbates Alzheimer’s disease pathology through neuronal CTSS signaling Journal of Neuroinflammation - Alzheimer’s disease (AD) exhibits a pronounced sex bias, with women facing disproportionately higher risk and more severe pathology. Postmenopausal estrogen... Metabolic reallocation in spinal cord oligodendrocytes drives chronic pain in mice through neuronal Aβ42 productionView quoted post on X
science.org/doi/10.1126/sc…
www.nature.com Injury-transduced oligodendrocytes modulate neuroinflammation and glial activation in diseased and... Nature Communications - This study identifies SerpinOLs, injury-responsive oligodendrocytes producing SERPINA3N, as a common cell state in disease and aging, which amplify neuroinflammation and... 
