@AbsalomNathan
academic.oup.com Follow the allosteric transitions to predict variant pathogenicity: a channel-specific approach We were intrigued to read a recent article by Brünger et al.1 outlining an innovative method to predict pathogenicity for variants in ion channel-encoding 
academic.oup.com Correlations of receptor desensitization of gain-of-function GABRB3 variants with clinical severity Lin et al. show that pathogenic GABRB3 variants can either increase or decrease desensitization of GABAA receptors. Reduced receptor desensitization at equ And we have a 🏆!! Serene El-Kamand our final year PhD student (with @RGamsjaeger) won a poster prize at #lorneproteins2023. Serene's the best and scouting for post-docs!View quoted post on X
