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Adam Cribbs

@AdamCribbs

CTO of Entelo Bio and Group leader University of Oxford
London, England entelo.bio Joined May 2013
1.3K Following 1K Followers 2.1K Posts

Latest posts 5

Adam Cribbs @AdamCribbs
Can AI agents actually do bioinformatics? The leaderboards say yes. We think a single accuracy score is the wrong measurement, so we built FlowBench to take it apart. Substack writeup: acribbs.substack.com/p/can-ai-agent…
acribbs.substack.com Can AI agents actually do bioinformatics? An aggregate accuracy score hides what an agent can and cannot do. Scoring the underlying capabilities separately shows that workflow planning is largely solved, while interpretation is not
Adam Cribbs @AdamCribbs
A single US export-control letter forced Anthropic to switch off its two best models worldwide. Overnight.

We've seen this before. In the 90s the US treated strong encryption as a munition, and lost.

The model is not the moat.

acribbs.substack.com/p/is-ai-now-th…
acribbs.substack.com Is AI now the new crypto war? The US government has just pulled Anthropic's two most capable models off the market on national security grounds. The 1990s saw the same logic applied to encryption. What does history tell us?
Adam Cribbs @AdamCribbs
🚀 New preprint on bioRxiv!
We benchmarked Nanopore direct RNA vs PCR-cDNA sequencing and found distinct 5′ & 3′ coverage biases that reshape transcriptome interpretation.
Read here 👉 biorxiv.org/content/10.110…
#RNAseq #LongRead #Nanopore
www.biorxiv.org Distinct 5′ and 3′ Coverage Biases Shape Transcriptome Interpretation in Nanopore Direct RNA versus... Long-read RNA sequencing enables isoform-resolved transcriptomics, but library preparation introduces systematic biases that shape biological interpretation. We benchmarked Oxford Nanopore’s two...