Adam Draper ⏻

Aditya Agarwal Verified account @adityaag · 4d

What makes an idea worth dedicating your life to?

I talked to @traestephens about Palantir, Founders Fund, Anduril, the risks of sky-high startup valuations, and what it really takes to build in defense.

Watch the full conversation at @spc now.

(00:30) Finding the Right Mission: Why Great Startup Ideas Find You
(02:57) From Government to Palantir: Finding the Right People and Culture
(11:44) Leaving Palantir: How Peter Thiel Recruited Trae to Founders Fund
(17:27) Learning Venture Capital: Why Trae Took 500 Startup Pitch Meetings
(21:19) Founders Fund's Investment Strategy: Why Only a Few Companies Drive Returns
(23:00) The AI Valuation Boom: Why Founders Must Be Careful About Raising Too Much
(30:06) Founding Anduril: How Trae Stephens and Palmer Luckey Built a Defense Tech Company
(34:18) Building Anduril's First Products and Competing With Defense Giants

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arian ghashghai Verified account @arian_ghashghai · Oct 31

The 🐐 of pre-seed deep tech (@AdamDraper) with a fan (me)

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Radiant Verified account @RadiantNuclear · Oct 29

Radiant has secured U.S. Department of Energy (@ENERGY) approval of its Documented Safety Analysis for Kaleidos, making it the only microreactor to be reviewed and approved by the DOE for full power operations.

The approval is not just for criticality, but for Radiant’s full power, full temperature testing at the Idaho National Laboratory. Radiant will test the complete reactor system using the same design it will manufacture at scale.

Next up in the path to commercialization: Readiness Review.

Read more here 🔗 radiantnuclear.com/news/radiant-s…

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Variety Verified account @Variety · Oct 29

Patrick Stewart, who will be remembered most for his roles as Captain Jean-Luc Picard on “Star Trek: The Next Generation” and as Professor Charles Xavier in the “X-Men” films, has died at 86.

variety.com/2026/tv/news/p…

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Mgoes (bio/acc 🤖💉) Verified account @m_goes_distance · Oct 27

this might be my last normal tweet before biotech goes vertical

i'm not a whistleblower. I don't work at Lilly, Novo or any of the big labs

but there is a massive shift happening in human biology right now.

it's sitting in press releases and almost nobody reads them

the last 6 months alone:

- a once-daily pill roughly doubled median survival in metastatic pancreatic cancer (13.2 vs 6.6 months)
- a one-time gene editing infusion cut hereditary angioedema attacks 87%, and 62% of patients stayed attack-free and off all other prevention for 6 months
- a one-time gene edit for cholesterol dropped LDL up to 62%, and it held for over a year
- a personalized mrna vaccine beat keytruda alone in a 1,137 patient melanoma phase 3
- retatrutide hit ~28% weight loss in a phase 3
- an ai-designed drug entered phase 3
- a pill that regrows hair passed its second phase 3
- an immunotherapy that could let some rectal cancer patients skip surgery, chemo and radiation just got fda approved
- a man lived 271 days off dialysis on a pig kidney
- human cells were caught passing chromosome-sized chunks of DNA to their neighbors, and it changes how the neighbors behave

we are on the verge of an era where the human body is a software problem and the update cycle gets shorter everyday

stick around, it's going to get weird

bio/acc

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