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Kamil Pabis

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@Aging_Scientist

Singapore based Aging Researcher.

@vita_dao, longevity advocacy, progress studies, city planning, open science, AI, democracy & economics of SE asia.
geroscience.substack.com Joined January 2017
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Kamil Pabis Verified account @Aging_Scientist
Yet another promising Parkinson treatment that made the disease worse(!) in a large phase II/III trial. Iron chelators failed. Now NAD failed too!

1/ Could AI predict such failures? I really doubt it. We can eke out some gains but it will not realistically solve the phase III problem.
2/ We need to run more trials and "fail faster". We need cheaper labor to do so and automation from AGI will be beneficial.
jamanetwork.com/journals/jama/…
jamanetwork.com Nicotinamide Riboside for Patients With Early-Stage Parkinson Disease This randomized trial assesses the effect of oral nicotinamide riboside treatment for 52 weeks vs placebo on clinical outcomes among patients with early Parkinson disease.
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Kamil Pabis Verified account @Aging_Scientist
The new AA data is interesting. It seems that as always google has a big model but the post-training just isn't there. High scores on omniscience but low scores on full and diverse AA index. Ant and OpenAI in a league of their own.