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Moritz Gerster

@BarleyMoritz

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Berlin, Germany moritz-gerster.com Joined November 2019
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Moritz Gerster @BarleyMoritz
Moritz Gerster @BarleyMoritz May 2, 2025
How does subthalamic activity relate to Parkinson’s disease symptoms? In a truly collaborative effort across #DBS centers, we aggregated a diverse dataset of invasive recordings from 119 patients.

Full article: doi.org/10.1101/2025.0…

Main findings 🧵⬇️
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Moritz Gerster @BarleyMoritz
Imagine you run an experiment with 50 subjects and find a significant effect just below p < 0.05.

Another research group tries to replicate your finding, so they also recruit 50 people.

If your methodology was perfect, what’s the chance the replication succeeds?

👇🧵
🧵 Why the obsession with p < 0.05 is hurting science. A meme. A truth. A reality check.
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Moritz Gerster @BarleyMoritz
Thank you @MPI_CBS for covering our study!

And thank you for fostering such an inspiring, intellectually vibrant, and genuinely supportive research environment — it was an exceptional place to do a PhD 🙏
Rauschen als Signal - @BarleyMoritz & Vadim Nikulin & @arnovillri entdeckten neue elektrische Signatur im #Gehirn von Patienten, die den Schweregrad von #Parkinson widerspiegelt: cbs.mpg.de/2412037/202510…
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