@BlurtonJonesLab
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Ending 2022 on a high note with the Bennett Lab’s first paper! Excited to finally share this work! TLDR: We (@FChrisBennett and @BlurtonJonesLab) engineered an inhibitor-resistant human CSF1R variant that can be used for microglial replacement. 🧵 below.View quoted post on X
Absolutely thrilled and so grateful to receive an ERC consolidator grant #ERCCoG!! ReplaceMi will engineer microglia - an amazing 🧠 cell - to treat brain disease! So much gratitude to my team members, mentors and loved ones! I♥️🧪@ERC_Research @VUBrussel europa.eu/!BvbtWJView quoted post on X
Adoptive transfer with microglia! Would love to see a mouse line with an analogous mutation in the future for examining effects of environmental vs cell-intrinsic shifts in microglial state.View quoted post on X
Ending 2022 on a high note with the Bennett Lab’s first paper! Excited to finally share this work! TLDR: We (@FChrisBennett and @BlurtonJonesLab) engineered an inhibitor-resistant human CSF1R variant that can be used for microglial replacement. 🧵 below.View quoted post on X
Even as we identify more diseases where #microglia replacement is an ideal therapeutic strategy, traditional transplant carries risk. We wanted to make it less dangerous and more robust. So proud of @FChrisBennett & @BlurtonJonesLab groups for this critical first step.View quoted post on X
