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BogerLab

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@BogerLab

synthesis of biologically active natural products, development of new synthetic methods, heterocyclic chemistry, DNA-agent interactions, antitumor antibiotics
The Scripps Research Institute scripps.edu/boger/ Joined March 2012
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Insights into Free Drug Release from Efficacious N-Acyl O-Aminophenol Duocarmycin Prodrugs | ACS Chemical Biology pubs.acs.org/doi/full/10.10…
Provocative observations made in wonderful collaborations that reveal an exclusive protein-mediated prodrug activation in cancer cells
pubs.acs.org Insights into Free Drug Release from Efficacious N‑Acyl O‑Aminophenol Duocarmycin Prodrugs Abstract. Acyclic and cyclic N-acyl O-aminophenol prodrugs of duocarmycin analogues were reported as members of a unique class of reductively cleaved prodr