Carina Seah, MD PhD

@CarinaSeah

Genetics, 🧠, stem cells, and social justice in science and medicine | 🇲🇾🇹🇭🇨🇳 | @SinaiMSTP @USCStemCell alum | she/her

New York, NY bit.ly/eGFRPetition Joined September 2013

618 Following 1.1K Followers 2K Posts

Latest posts 5

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Carina Seah, MD PhD @CarinaSeah Oct 21, 2022

What does it mean to model stress in a dish? My first first-author paper of my PhD is out today in @NatureNeuro! 🧵 (art by the incredible @jsj8duke) go.nature.com/3grbgGq

Carina Seah, MD PhD @CarinaSeah Feb 8, 2024

So cool to see biological mechanisms of stress susceptibility being ironed out!

Scott Russo @ScottRussoPhD Feb 7, 2024

Interested in #neuroimmunology and #depression? Check out our new paper led by @FlurinCathomas in @Nature. nature.com/articles/s4158…

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Carina Seah, MD PhD @CarinaSeah Nov 6, 2023

We had a lab baby shower today and here are some of the lab-themed children’s activity book pages I made that a totally normal child would totally fill out

Kids activity book page matching the SNP to the eGenes based on colors

Children’s activity book page showing connect the dots to determine if the graph shows an interaction

Children’s activity book page asking child to fill out all about me, with my favorite gene, coding language, tissue, statistical test, and environment

Carina Seah, MD PhD @CarinaSeah Sep 11, 2023

Good morning, @CNS_Update! Honored to share what we’ve found on the impact of cerebral atherosclerosis on the brain… and on one particular cell type in particular 👀🧠

Mount Sinai Neurosurgery Verified account @MountSinaiNeuro Sep 11, 2023

⏰Set your alarm for the #2023CNS Sunrise Sessions! #Neurosurgery med student @CarinaSeah will present her Cerebrovascular research on the transcriptomic analysis of the post-mortem brain in intracranial atherosclerosis implicates interferon signaling! @CNS_Update #ICAS #stroke

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Carina Seah, MD PhD @CarinaSeah Apr 27, 2023

How do our individual genetic differences lead to different biological responses to trauma? I’m presenting my work on gene-trauma interactions at #SOBP2023! Come learn about the often messy but sometimes insightful ways we’re trying to disentangle how we respond to our experience

At this point, many of us know that trauma is encoded in the body— it physiologically changes how we function. But why do different people experience and react to trauma so differently?

I answer this question two ways— first by looking at the biology of post mortem brains from people who have been exposed to severe traumas. Secondly by modeling stress exposure in a dish, by making neurons from skin cells from people with and without PTSD and exposing them to a chemical stressor. Both are imperfect ways to study complex responses and complex biology, but from looking at what both models have in common, we might be able to decipher how our genetics impacts stress response.