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Peter Cashin

@CashinPtr

Associate Professor of Surgery, family man, house church, HIPEC research, Peritoneal Surface Oncology Research, Proteomics in postoperative complications
Joined August 2022
64 Following 89 Followers 290 Posts

Latest posts 5

Peter Cashin @CashinPtr
Slightly disheartening! More studies need to look att biological mechanisms of tissue healing. Perhaps more relevant prehab interventions can be found… microbiome interventions seem to show some promise.
BJS Verified account @BJSurgery Mar 2
Effects of Multimodal Prehabilitation on High-impact Surgery Outcomes: a prospective stepped-wedge, hospital-wide implementation study
➡️ doi.org/10.1093/bjs/zn…

In this hospital-wide stepped implementation study, multimodal prehabilitation showed partial adherence and did not reduce postoperative Clavien–Dindo grade ≥2 complications or length of hospital stay in a heterogeneous surgical population
Although no statistically significant effects were observed, the confidence intervals included potentially clinically meaningful differences, meaning a relevant effect cannot be excluded
Exploratory analyses suggested a trend towards fewer complications in patients undergoing gastrointestinal oncological surgery, supporting further evaluation of targeted prehabilitation in high-risk populations

Work by Luuk D Drager, MD , Femke Atsma, PhD , Dieuwke Strijker, PhD , Linda A G van Heusden-Scholtalbers, MSc , Monique J M D van Asseldonk, MSc , Jonas Rosenstok, MA , Joost P H Seeger, PhD , Sjors Verlaan, PhD , Laurien M Buffart, PhD , Prof Cornelis J H M van Laarhoven, PhD , Baukje van den Heuvel, PhD on behalf of , the F4S PREHAB Collaborative Group

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Peter Cashin @CashinPtr
The role of systemic adjuvant chemo after CRS and HIPEC in appendix cancer appears unclear, perhaps ineffective?
Gagan Brar @gagan_brar24 Jan 20
⭐️Just published - The role of systemic chemotherapy to CRS/HIPEC in patients with appendiceal cancers
⛔️ No role for systemic chemo
❓Where does chemo fit❓
@jpshen_md #GI26 Abst#840 also shows no benefit of AC in early stage dz
clinical-colorectal-cancer.com/article/S1533-…
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Peter Cashin @CashinPtr
Something to test in an RCT? Perhaps an ERAS program enhancement?
@ConsorciCSI Intravenous lidocaine infusion compared to thoracic epidural analgesia in cytoreductive surgery with or without heated intraperitoneal chemotherapy. A retrospective case-cohort study pubmed.ncbi.nlm.nih.gov/36437212/
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