Brian Edlow

@ComaRecoveryLab

The Lab for NeuroImaging of Coma and Consciousness is dedicated to promoting recovery from severe brain injury.

Massachusetts General Hospital ComaRecoveryLab.org Joined March 2016

526 Following 3.9K Followers 1.9K Posts

Latest posts 5

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Brian Edlow @ComaRecoveryLab May 31, 2019

We are proud to release a 100 micron MRI scan of the human brain. Preprint on biorxiv.org/cgi/content/sh…. Videos on youtube.com/playlist?list=…. Dataset will be available in native space and MNI space at datadryad.org and integrated into lead-dbs.org. [1/2]

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Brian Edlow @ComaRecoveryLab Apr 18

Two new tools to map the human brainstem:

nuclei: onlinelibrary.wiley.com/doi/abs/10.100…
bundles: pnas.org/doi/10.1073/pn…

code: surfer.nmr.mgh.harvard.edu/fswiki/AANSegm…
github.com/markolchanyi/B…

@olchanyi @JuanEugenioIgl1 @MGHMartinos @MGH_CNTR @MGBResearchNews @MIT

Brian Edlow @ComaRecoveryLab Sep 20, 2025

Congratulations to @bu_cte @BU_Tweets @VABostonHC on this landmark contribution to the field of chronic traumatic encephalopathy (CTE):

nature.com/articles/s4158…

Elegant and groundbreaking work, with substantial public health implications.

www.nature.com Repeated head trauma causes neuron loss and inflammation in young athletes Nature - Repetitive head impacts from contact sports are associated with brain inflammation, vascular damage and neuron loss that are independent of hyperphosphorylated tau pathology.

Brian Edlow @ComaRecoveryLab Mar 11, 2025

Visualizing Effective Connectivity in the Human Brain

Preprint: biorxiv.org/content/10.110…
Code: github.com/ComaRecoveryLa…
YouTube video: youtu.be/V0hqs-noYNg
Download video & figures: zenodo.org/records/149748…

Led by #XanderAtalay & #TeoFecchio

@MGH_CNTR @MGHMartinos @MGHNeuroICU

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Brian Edlow @ComaRecoveryLab Oct 23, 2024

For years, many of us used traumatic microbleeds on MRI to prognosticate in the ICU for pts w/ severe TBI.

We assumed microbleed = axonal injury.

This assumption was incorrect: medrxiv.org/content/10.110…

www.medrxiv.org TRAUMATIC MICROHEMORHAGES ARE NOT SYNONYMOUS WITH AXONAL INJURY Diffuse axonal injury (DAI) is caused by acceleration-deceleration forces during trauma that shear white matter tracts. Susceptibility-weighted MRI (SWI) identifies microbleeds that are considered...