Sagar

@CryoSagar

Fiddling with the code and instruments for CryoET in between coffee, good food. Opinions are my own.

#teamtomo Joined July 2017

323 Following 328 Followers 131 Posts

Latest posts 5

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Sagar @CryoSagar Dec 29, 2024

Hey #teamtomo checkout our team science approach to #cellbio #cryoET

I can’t thank @bengeliscious enough for this one 😍😍

Awesome team science from @MPI_Biochem @biozentrum @thermosciEMSpec and more

Signing off Twitter with a good one

biorxiv.org/content/10.110…

www.biorxiv.org Towards community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydom... In situ cryo-electron tomography (cryo-ET) has emerged as the method of choice to investigate structures of biomolecules in their native context. However, challenges remain in the efficient product...

Sagar @CryoSagar Sep 6, 2024

Order in Chaos brought to you by #TOMOMAN with generous support from @williamnwan #teamtomo #cryoet #insitu #opensource

biorxiv.org/content/10.110…

www.biorxiv.org TOMOMAN: a software package for large scale cryo-electron tomography data preprocessing, community... Cryo-electron tomography (cryo-ET) and subtomogram averaging (STA) are becoming the preferred methodologies for investigating subcellular and macromolecular structures in native or near-native...

Florent Waltz @FlorentWaltz Sep 6, 2024

Same for @CryoSagar and STOPGAP, which was instrumental here. But it still remains really difficult to make this kind of analysis because the processing pipeline is not as streamlined as in SPA. Actually, sometimes it really looks like that:

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Sagar @CryoSagar Apr 13, 2024

#STOPGAP is now published 🥳🥳
With @williamnwan and Twitter less Jonathan Wagner
I must say, the peer review @ActaCrystD was as it should be, relevant, fast 😍
One of many to be published together with awesome @williamnwan
#teamtomo #opensource #cryoEM

Will Wan @williamnwan Apr 13, 2024

Our manuscript for STOPGAP is now out in @ActaCrystD! It was great working with @CryoSagar
and twitterless Jonathan Wagner.

journals.iucr.org/d/issues/2024/…
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Sagar @CryoSagar Apr 10, 2024

Now all we need some is #communitycompute to mine all this data together! And visualize life at molecular detail! #cryoET goes #bigdata
Any thoughts from awesome people at @GoogleDeepMind @AmazonScience @nvidia @NVIDIAAI
time to go brrrrr!!!!

Sagar @CryoSagar Apr 10, 2024

Hey #teamtomo Here is EMPIAR-11830!
Some 1800 tomograms from awesome #Chlamy (Chlamydomonas reinhardtii) using large scale #cryoET!
In addition , all the metadata and preprocessing as #minimalproject to get you started right away! #TOMOMAN #bigdata #communityscience 1/
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Sagar @CryoSagar Apr 10, 2024

Hey #teamtomo Here is EMPIAR-11830!
Some 1800 tomograms from awesome #Chlamy (Chlamydomonas reinhardtii) using large scale #cryoET!
In addition , all the metadata and preprocessing as #minimalproject to get you started right away! #TOMOMAN #bigdata #communityscience 1/

EMBL-EBI @emblebi Apr 10, 2024

The new @EMDB_EMPIAR cryo-electron tomography (cryo-ET) browser allows you to see proteins up close in the cellular environment.

Over 1,800 high-resolution reconstructed tomograms from cryo-plasma-FIB milled Chlamydomonas reinhardtii cells are available.

ebi.ac.uk/about/news/ann…

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