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๐จ New preprint from my lab! Work led by @ninabarr95 shows:
1) In human cerebellar organoids- RNA decay controls developmental timing.
2) EXOSC3 variants disrupt when and where genes are expressed.
3) Purkinje cells take the biggest hit.
#RNADecay ๐ง
biorxiv.org/content/10.648โฆ
1) In human cerebellar organoids- RNA decay controls developmental timing.
2) EXOSC3 variants disrupt when and where genes are expressed.
3) Purkinje cells take the biggest hit.
#RNADecay ๐ง
biorxiv.org/content/10.648โฆ