Daniel Batlle

@Dan_Batlle

Nephrologist at Northwestern University. Physician scientist with diverse research interests, ACE2. Proud grandfather. Soccer, go FC Barcelona!

Chicago, IL Joined February 2018

1.6K Following 2.1K Followers 5.6K Posts

Latest posts 5

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Daniel Batlle @Dan_Batlle May 30, 2022

Happy to see this paper out in Cell and grateful to the several collaborators that made it possible.

Cell @CellCellPress May 30, 2022

In the latest issue! Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity dlvr.it/SRJStm
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Daniel Batlle @Dan_Batlle Oct 15

It is not only how fast or when but how. Using a vaptan with regulated water intake is a more physiologic approach : eliminate water excess rather than giving sodium
Studies in normal volunteers ( whithout hyponatremia ) show this nicely See Weiss et al @Sweis_NWG

journals.physiology.org/doi/full/10.11…

journals.physiology.org Increasing plasma sodium with Tolvaptan under regulated water intake: comparison with hypertonic... In the treatment of hyponatremia, there is a potential risk of osmotic demyelination due to an excessively rapid rise in plasma sodium. We reasoned that a controlled rate of sodium increase could be...

Jonathan Chávez Verified account @JonathanNefro Oct 15

Nueva propuesta de expertos para la corrección de hiponatremia, consiste en 3 pasos justificados por la evidencia reciente

1-estratificación riesgo (valor de Na)
2-corrección con base en factores para desmielinización osmótica
3-reconocer la impresión de la corrección

JASN 2026
10.1681/ASN.0000001270

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Daniel Batlle @Dan_Batlle Oct 4

Thank you for posting our paper and the nice analysis of the findings , why was the answer surprising ? We should not be so affraid to use a vaptan particularly at a low dose ( actually the doses of tolvaptan used in our study were high ) to correct hyponatremia if water intake is regulated

Nephrology Journal Club @NephJC Oct 3

Can tolvaptan keep up with 3% saline?

This within-subject study in healthy volunteers delivered a surprising answer - and a few eyebrow-raising physiology twist. Dive in #NephJC

✍️ by @DrSaiVani1

nephjc.com/news/tolvaptan…
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Daniel Batlle @Dan_Batlle Oct 2

Proud of you Ahmed!

Ahmed Ismail, MD Verified account @A_Ismail_MD Oct 1

It was a pleasure to present my research at the ACP Virginia chapter.
Grateful to my mentors for their support, guidance, and inspiration!

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Daniel Batlle @Dan_Batlle Oct 1

Pleased to post our paper by @Sweis_NWG et al. published in the October issue of JASN @ASNKidney on metabolic acidosis in CKD using estimated arterial pH, pCO2, and bicarbonate from venous blood (doi: 10.34067/KID.0000001113).

ovid.com/10.1681/ASN.00…

@NUFeinbergMed @NU_Nephrology @NorthwesternMed