Di Antonio Research Group

@DiAntonioLAB1

We are a Chemical-Biology group investigating DNA structures and dynamics based at Imperial College Chemistry.

Imperial College London imperial.ac.uk/diantonio-rese… Joined May 2019

473 Following 1.7K Followers 1.5K Posts

Latest posts 5

Di Antonio Research Group @DiAntonioLAB1 Dec 17, 2025

Great to see ATENA covered in @cenmag! This is a testament to the great work led by Sabrina and collaborators @DrZoeWaller and Jay. #stillwerise cen.acs.org/biological-che… via @cenmag

cen.acs.org New CRISPR-based tool targets DNA secondary structures with sequence specificity The tool, called ATENA, binds a Cas9 protein to ligands that interact with specific DNA structures

Di Antonio Research Group @DiAntonioLAB1 Dec 12, 2025

Want to modify CRISPR-proteins with small molecules? Check out our new method ATENA just published in @NatureComms! ATENA enables single-site engagement in the genome with unprecedented control and selectivity!

nature.com/articles/s4146…

www.nature.com Chemically modified CRISPR-Cas9 enables targeting of individual G-quadruplex and i-motif structur... Nature Communications - Targeting individual DNA secondary structures in the genome with small molecules is challenging. Here, the authors develop ATENA, a CRISPR-based platform for targeting...

Di Antonio Research Group @DiAntonioLAB1 Nov 24, 2025

Thank you @ListerInstitute!

The Lister Institute of Preventive Medicine @ListerInstitute Nov 24, 2025

Impressive number of Lister community members in @Clarivate's Highly Cited Researchers 2025. Our first shoutout to current #ListerFellows

🥇 Marco di Antonio @DiAntonioLAB1
🥇 Ravi Gupta @GuptaR_lab

Congrats on your highly influential research 👏

clarivate.com/highly-cited-r…

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Di Antonio Research Group @DiAntonioLAB1 Nov 13, 2025

I am truly honoured to be listed amongst the top 1% researchers featuring the 2025 highly cited researchers list generated by @Clarivate. This achievement reflects the excellent work of my group members, they are the best! @imperialcollege #highlycited2025

Clarivate @Clarivate Nov 12, 2025

Discover the researchers shaping science and society.

#HighlyCited2025 is live: ow.ly/y23050XohmV

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Di Antonio Research Group @DiAntonioLAB1 Sep 18, 2025

We are hiring! We are looking for a PDRA to work on the epigentics of breast cancer dormancy through chemical biology and genomics approaches. This is a 3-year and aimed at a chemical biologist or a biologist. Please apply using the link below 👇👇👇

imperial.ac.uk/jobs/search-jo…

www.imperial.ac.uk Description Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...