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DiMicheleLAB

@DiMicheleLAB1

Lorenzo Di Michele's research group @cebcambridge @MemBiophysIC @fabriCELL_UK #Nanotechnology #SyntheticCells #Biophysics
Cambridge, United Kingdom dimichelelab.org Joined May 2018
668 Following 1.5K Followers 443 Posts

Latest posts 5

DiMicheleLAB @DiMicheleLAB1
Great new @J_A_C_S paper by @rogerrubio. Please check it out!
Roger Rubio Sánchez @rogerrubio Sep 8, 2025
Really happy to see this published in its final form @J_A_C_S! 🧬 In this paper, we introduce a new class of biomimetic receptors to host functionality in synthetic cell membranes

Elita Peters @dianatanasedt @DiMicheleLAB1

pubs.acs.org/doi/10.1021/ja…
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DiMicheleLAB @DiMicheleLAB1
Very excited about this one! Sequence-specific interactions between dsDNA accurately quantified + modelled 🧬! New preprint by Andy Stannard + Ehud Haimov, @JonathanGHedley from Alexei Kornyshev's team and many others. Let us know what you think!

chemrxiv.org/engage/chemrxi…
chemrxiv.org Direct evidence and quantification of homologous recognition between DNA duplexes | ChemRxiv Stretches of double-stranded DNA sharing the same sequence can recognise each other in cells. This phenomenon, known as homologous recognition, is essential for DNA recombination and repair. Yet, its...
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DiMicheleLAB @DiMicheleLAB1
Thrilled to share this new Adv. Sci. paper by @dianatanasedt with Dino Osmanovic @rogerrubio Layla Malouf and Elisa Franco. We demonstrate a modular approach to program internal phase separation in DNA condensates 1/n
advanced.onlinelibrary.wiley.com/doi/10.1002/ad…
advanced.onlinelibrary.wiley.com Internal Phase Separation in Synthetic DNA Condensates The modular, programmable system of DNA nanostructures developed provides programmatic control over multiphase condensate behavior, enabling mapping onto a predictive Flory-Huggins model. This...
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DiMicheleLAB @DiMicheleLAB1
Thrilled to share our latest preprint on expressing synthetic organelles made from RNA nanostructures in bacterial cells. Great work from @BrianNgSH, Catherine Fan, @milandordevicc, Adam Knirsch, coll. Graham Christie @TakinoueLab @CicutaGroup 1/n

biorxiv.org/content/10.110…
www.biorxiv.org Expression of nano-engineered RNA organelles in bacteria Designing synthetic biomolecular condensates, or membrane-less organelles, offers insights on the functions of their natural counterparts, and is equally valuable for cellular and metabolic enginee...
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