Differentiation Journal

@Diff_Journal

Flagship journal of @Intlsocdiff. Published by #Elsevier for 40+ years. All things relating to differentiation, development, stem cells and regeneration

journals.elsevier.com/differentiation Joined December 2021

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Differentiation Journal @Diff_Journal Apr 22, 2024

Differentiation is the flagship journal of the International Society of Differentiation (ISD) @intlsocdiff. We are a multidisciplinary journal focusing on principal subject areas of cell and tissue differentiation, embryonic development, cellular structure and function, and 1/4

Differentiation Journal @Diff_Journal 3d

Xunwei Liu et al. established a single-cell transcriptomic atlas of zebrafish thrombocytes and integrated it with mammalian megakaryocyte datasets to enable a cross-species comparative analysis of megakaryocyte–platelet lineage development. Learn more: sciencedirect.com/science/articl…

Differentiation Journal @Diff_Journal Oct 30

Dianshan Ke et al. propose that targeted interventions aimed at enhancing STAT1 phosphorylation may serve as a promising therapeutic strategy for osteoclastogenic bone loss. Learn more: sciencedirect.com/science/articl…

Fig. 7. The working model regarding the relationship between STAT1 phosphorylation, regulated OCP apoptosis and osteoclastogenesis under RANKL induction. Briefly, under RANKL induction, STAT1 is phosphorylated at the Ser727 site in OCPs, which dominates the pro-apoptotic effect of STAT1 in OCPs through STAT1-p53 interaction and subsequent transcription to Bax-RNA; the above process inhibits RANKL-induced osteoclastogenesis.

Differentiation Journal @Diff_Journal Oct 14

Deadline approaching 🚨 Submit to the "Enteric nervous system development and repair" by October 31! Learn more and submit: sciencedirect.com/special-issue/…

Keywords:
• Neural circuits
• Enteric progenitor cell
• ENS regeneration
• ENS neurons
• ENS glial cells

Differentiation Journal @Diff_Journal Oct 7

Findings from Raziyeh Taghizadeh Ghavamabadi et al. suggest that resveratrol may support cardiac induction while only partially attenuating the cytotoxic effects of 5-azacytidine. Learn more: sciencedirect.com/science/articl…

Fig. 2. A. MSC on day 3. Cultures were terminated on day 3 as Mesenchymal Stem Cells (MSCs) achieved confluency, a point beyond which further culture was not feasible. B. Res-only group on day 21. C. 5-aza group on day 21. D. Res 5 group on day 21. E. Res 10 group on day 21. F. Res 20 group on day 21. Perinuclear clear regions that appeared to be consistent with cytoplasmic lipid droplet accumulation are indicated by black arrows, and cell-to-cell junctions morphologically resembling intercalated disc-like structures are highlighted by a black circle. The magnification ×20.