Very excited about this study in @EmboMolMed, where we show that KRAS mutations drive glycolytic reprogramming of the endothelium in sporadic brain arteriovenous malformations. We show a synergistic impact of targeting glycolysis and MEK. link.springer.com/article/10.103…
link.springer.com KRAS-dependent glycolytic reprogramming of endothelial cells in sporadic arteriovenous malformations EMBO Molecular Medicine - Somatic activating KRAS mutations in endothelial cells are the predominant cause of sporadic brain arteriovenous malformations (bAVMs) and also occur in sporadic... 
