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GenomeTDCC

@GenomeTDCC

NHGRI Technology Development Coordinating Center
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Farmington, CT genometdcc.org Joined October 2021
379 Following 335 Followers 451 Posts

Latest posts 5

GenomeTDCC @GenomeTDCC
Captify: A new platform to study chromatin readers in the nucleosome context.
Recently published in Nucleic Acids Research, the folks at @epicypher discuss development & integration of these easily adoptable biochemical and genomic tools
doi.org/10.1093/nar/gk…
academic.oup.com Nucleosome context regulates chromatin reader preference Abstract. Chromatin is more than a simple genome packaging system but rather locally distinguished by histone post-translational modifications (PTMs) that
GenomeTDCC @GenomeTDCC
Spatial Biology just leveled up!
@SStevenWang introduces RAEFISH in this latest publication highlight
Whole-transcriptome imaging at single-molecule resolution. See 20,000+ RNAs light up in cells and tissues. Plus direct gRNA detection for CRISPR screens
youtube.com/watch?v=P2j6ax…
www.youtube.com Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution Discover RAEFISH: A Breakthrough in Spatial TranscriptomicsIntrod...
2 replies 6 reposts 20 likes 3.7K views View on X
GenomeTDCC @GenomeTDCC
What if doing something poorly could lead to something great? Sometimes tradeoffs lead to breakthroughs.
Rob Mitra, @GenomeInstitute, dives into the evolution of genome tech, next-gen sequencing and how his lab is fighting rising drug costs with innovation
youtube.com/watch?v=C8U5WD…
www.youtube.com Technology Development for Genome Analysis - Rob Mitra, PhD What if doing something poorly could lead to something truly ground...