Gordan Lauc

@GordanLauc

Scientist and entrepreneur from Zagreb, Croatia. Professor at Uni Zagreb and founder and CEO of Genos, the global leader in high-throughput glycomics.

Republic of Croatia genos-glyco.com Joined July 2017

360 Following 44K Followers 2K Posts

Latest posts 5

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Gordan Lauc @GordanLauc Jan 3, 2025

I am frequently asked to explain the main diffence between glycan and epigenetic tests for monitoring individual patients. Short version of the answer is available in this 5 min clip from the plenary lecture I had at the 2024 Longevity Fest in Las Vegas.

5:08

Gordan Lauc @GordanLauc May 25

Just published in Nature Chemical Biology nature.com/articles/s4158…
If you do not have access to full text, I am adding a link to read only version in comments

www.nature.com Large glycomics datasets as a tool to understand the function of glycans Nature Chemical Biology - Recent technological advances are enabling a growing number of large-scale glycomics studies. This Review discusses the challenges in high-throughput glycoanalytical...

Gordan Lauc @GordanLauc Apr 24

I published over 300 papers so far, but only a few of them were as comprehensive this one. We report acceleration of glycan aging in many disease, show prediction of mortality, identify some interventions that can reverse glycan aging,etc... Have a look
medrxiv.org/content/10.648…

www.medrxiv.org The Immunoglobulin G Glycome: A Modifiable Biomarker and Functional Effector of Aging, Disease, and... Glycosylation is a key structural modification of immunoglobulin G (IgG) that modulates its effector functions and has multiple roles in balancing inflammation. Altered IgG glycosylation has been...

Gordan Lauc @GordanLauc Nov 23, 2025

The complexity of protein glycosylation is overwhelming and we are only starting to understand it. However, without understanding glycosylation we simply cannot understand any aspect of multicellular life...
nature.com/articles/s4158…

www.nature.com Structural basis of regulated N-glycosylation at the secretory translocon Nature - The structural mechanism of a natively isolated GRP94 folding intermediate tethered to a CCDC134-bound translocon is described, revealing how the nascent chain remodels the translocon to...

Gordan Lauc @GordanLauc Nov 15, 2025

Protein glycosylation literally enabled the development of multicellular organisms and through the Human Glycome Project we are trying to understand it. Have a look at this presentation to see what we learned from the first 250,000 analysed glycomes youtu.be/sx4AzP6UKQ0?si…

www.youtube.com Gordan Lauc - What did we learn from the first 250,000 human glycomes Presentation from the 6th Human Glycome Project Meeting, Split, Cro...