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I am excited to share our new work from @CreminsLab on genome’s structure-function relationship in post-mitotic human neurons and a neurological disease context (biorxiv.org/content/10.110…)! (1/n)
www.biorxiv.org A multi-looping chromatin signature predicts dysregulated gene expression in neurons with familial... Mammalian genomes fold into tens of thousands of long-range loops, but their functional role and physiologic relevance remain poorly understood. Here, using human post-mitotic neurons with rare... 
