JAMA+ Trials

This month's JAMA+ Trials Theme of the Month focuses on feasibility studies and pilot trials, which are designed to assess whether investigators can successfully conduct a larger, definitive investigation.

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How should extension studies be interpreted?

46.4% of JAMA+ Trials poll respondents said they provide important information about long-term safety and treatment durability.

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#ClinicalTrials #ClinicalResearch

💬 Editorial by JAMA+ Trials EIC Alison Huang, MD, MAS, and Lehana Thabane, PhD: #ClinicalTrials feasibility studies can inform if larger trials should proceed; small pilot studies may provide imprecise estimates of recruitment, retention, and adherence.

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In a phase 3 randomized clinical trial published in @JAMAInternalMed, #elinzanetant was assessed in postmenopausal women aged 40 to 65 years seeking treatment for moderate to severe #Menopause-associated vasomotor symptoms.

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How should extension studies to clinical trials be interpreted?

💭 Cast your vote in the latest JAMA+ Trials poll and share your perspective.

📊 Take the poll: ja.ma/4ilvgH3