Great article by @tran_khoa and colleagues! Enjoyed the read
SIRT7 regulates NUCKS1 chromatin binding to elicit metabolic and inflammatory gene expression in senescence and liver aging dlvr.it/TLSsdNView quoted post on X
Latest posts 5
Our new manuscript is now available as a preprint!⛅️
biorxiv.org/content/10.110…
1/ Here, we describe a novel BMAL1-YAP complex in epidermal cells, which is hijacked during ageing to control the expression of up-regulated inflammation genes through enhancer binding.🧵
biorxiv.org/content/10.110…
1/ Here, we describe a novel BMAL1-YAP complex in epidermal cells, which is hijacked during ageing to control the expression of up-regulated inflammation genes through enhancer binding.🧵
www.biorxiv.org BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis Ageing is characterised by persistent low-grade inflammation that is linked to impaired tissue homeostasis and functionality. However, the molecular mechanisms driving age-associated inflammation... Go check it out!💯
Circadian clocks constantly communicate to preserve tissue homeostasis, but ageing compromises the mechanisms that enable this crosstalk. Want to learn more? In our new review, @JacobSmithSci, Pura, Salva and take a dive into all things clock communication nature.com/articles/s4158…View quoted post on X
Very happy to have presented our project on "BMAL1 and YAP functional interplay in the epidermis" on today's #ISSCR2024 poster session in Hamburg. 🧬
Hope to see you all there!!😊
On March 21st we will be raising money for @pulserascandela8
Their goal is to fund research on childhood cancer. You will be able to get their bracelets at the bakesale 🥳
Join us and support a great cause while you enjoy delicious homemade treats 🤗View quoted post on X
