Excited to share our latest perspective on how the principles that drive success in distributional semantics can analogously help our understanding of gene function! cell.com/cell-systems/f…
Jason Kwon
@JKwonBio
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Ever wondered if your favorite protein is amenable for targeting via degrader approach? @DanB0nD1 et al developed an elegant plug-n-play resource to profile the capacity for small molecule-mediated degradation of your POI through a panel of degron tags. nature.com/articles/s4146…
Happy to share our latest work now out in @nature. At long last, we resolved the structure of the SHOC2-RAS-PP1C complex and integrated this work with deep mutational scanning to comprehensively evaluate #SHOC2 structure and function. 🧵(1/n)
nature.com/articles/s4158…
nature.com/articles/s4158…