Tonight, we held our annual Paper of the Year meeting, during which we celebrated the great chemistry published in 2025. This year’s winner was the Stereoretentive Radical Cross-Coupling from @BaranLabReads nature.com/articles/s4158…
www.nature.com Stereoretentive radical cross-coupling Nature - Readily accessible enantioenriched sulfonylhydrazides and low loadings of an inexpensive achiral Ni catalyst can be used to control the stereochemical outcome of radical cross-coupling. Jacobsen Lab
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Congratulations to @GabrielLovinger and Marcus Sak @msh_yi on their paper in @Nature! A HBD catalyst accelerates an SN2 pathway despite H-bonding to the nucleophile by preorganizing the ion pair into a reactive conformation, just like an enzyme would!
nature.com/articles/s4158…
nature.com/articles/s4158…
Didn’t know a Wittig reaction could be enantioselective? Check out the latest instalment of our work in chiral lithium isothiourea boronates! pubs.acs.org/doi/10.1021/ja…
Congratulations to our G2s Timur (@timur_adrianov), Agata (@agatabikovtseva), Marcus (@msh_yi), and Jonathan on passing their qualifying exams! Looking forward to the all the science you accomplish in the years to come!