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Sebastien Jacquemont

@JacquemontSeb

Geneticist. Investigating links between genomic variants, neuroimaging phenotypes, cognition, and risk for psychiatric conditions.
University of Montreal Joined May 2015
35 Following 241 Followers 68 Posts

Latest posts 5

Sebastien Jacquemont @JacquemontSeb
Monumental work by an awesome student !!!!
Clara Moreau @ClaraMoreau9 May 25, 2021
Our new preprint is now online! 🎉
#Polygenicity #Pleiotropy
'Atlas of functional #connectivity relationships across rare and common genetic variants, traits, and #psychiatric conditions'
@JacquemontSeb @pierre_bellec @ThomasBourgeron @PTenigma @meetkd007
medrxiv.org/content/10.110…
https://www.medrxiv.org/content/10.1101/2021.05.21.21257604v1
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Sebastien Jacquemont @JacquemontSeb
Neuroimaging of large effect-size genetic risk for neuropsychiatric disorders is gaining traction! This robust effect and can be leveraged to link molecular function to large-scale brain networks.
Clara Moreau @ClaraMoreau9 Apr 6, 2021
Our new review in Current Opinion in Genetics & Development: Structural and functional brain alterations in #CNVs overlap with those found in idiopathic #psychiatric conditions but effect sizes are 2 to 5 fold larger @Winkytheelf @JacquemontSeb @meetkd007
sciencedirect.com/science/articl…
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Sebastien Jacquemont @JacquemontSeb
#JobAlert: Are you ready to tackle brain function and risk for psychiatric disorders using large-scale sequencing, neuroimaging, and cognitive datasets! @PTenigma, @G2MH_Network, @bogglerapture, @G2MH_Network
Guillaume Dumas @introspection Mar 23, 2021
Ready to "reverse-engineer" the human brain in Montréal?

🚨#JobAlert: Post-Doc/PhD in psychiatric neurogenomics — fully funded!

Position in collaboration between @JacquemontSeb, @danilobzdok & @ppsp_team

academicpositions.com/ad/universite-… #PleaseRT
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Sebastien Jacquemont @JacquemontSeb
Study is out! High-confidence LoF mutations in a large proportion of ASD-genes show moderate relative risk for ASD and are observed in unaffected individuals. Yes, these variants are deleterious, but we overestimate their impact in the clinic!
Thomas Rolland @ThomasRolland75 Feb 14, 2021
What is the profile of carriers of autism-associated mutations in the general population? We identified such mutations among >10K autistic and >100K control individuals, but instead of focusing on the "patients", we looked at the non-autistic individuals.👉medrxiv.org/content/10.110…
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Sebastien Jacquemont @JacquemontSeb
Great but can you re-introduce the color coding identifying the type of variant : LoF versus missense? That was super practical !
Genome Aggregation Database @gnomad_project Jan 26, 2021
The #gnomAD browser now displays more #ClinVar data!

New features include:
- ClinVar track includes all classifications
- Clinical significance, plus links to ClinVar, added to the variant table
- ClinVar details added to the variant page
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