James Fasham

@JamesFasham

🧬👨‍⚕️Academic Consultant in Clinical Genetics 💬 Social media chair: @ESHGsociety. 🤖 @DiseaseGenes bot creator #Genetics #Genomics #RareDisease

Exeter, England Joined July 2015

2.6K Following 2.9K Followers 2.6K Posts

Latest posts 5

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James Fasham @JamesFasham Jul 19, 2024

3 pieces of big news:

✅I have completed my CCT in Clinical Genetics
👨‍⚕️I have accepted a consultant position in Exeter
🧑‍🎓@ExeterBRC have offered me a fellowship to continue my research at @UniofExeter

V grateful to everyone who has helped me on this (15 year!) journey.

James Fasham @JamesFasham Jul 16

DECIPHER continues to be actively developed Your feedback will help the team understand users’ experiences and identify possible improvements. Ive just done it, it takes less than 5 mins!

The DECIPHER Project @deciphergenomic Jul 14

The annual DECIPHER user survey is now available ! Please, help us to improve DECIPHER by taking 5 minutes to answer. docs.google.com/forms/d/e/1FAI…
This is a new survey so don’t hesitate to answer it even if you had completed it last year.

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James Fasham @JamesFasham Jun 16

Danny Cohn (Amsterdam UMC)

💊 Permanent prekallikrein silencing using in vivo CRISPR-Cas9 for hereditary angioedema

Phase 3 trial: 87% ⬇️ in attacks vs placebo

62% attack & therapy-free over 6 months.

📄 Hot off the press in time for #ESHG2026! nejm.org/doi/full/10.10…

James Fasham @JamesFasham Jun 16

Rebecca Ahrens-Nicklas (CHOP)

💊 First-in-human personalised base editing for CPS1 deficiency

Bespoke adenine base editor delivered by liver-targeted LNPs designed, manufactured, tested & given under expanded access within months of birth.

pubmed.ncbi.nlm.nih.gov/40373211

#ESHG2026

James Fasham @JamesFasham Jun 15

#eshg2026