Janet Pope
@Janetbirdope
not so new at tweeting but always opinionated
59 Following 21K Followers 12K Posts
Latest posts 5
#Sjogren鈥檚 is no longer a
#dry #Rx landscape
Which to choose in future?
#Ianalumab
#dazodalibep
DIff #MOA
#CD40L
#CD20 deleted+ altered B cell
Signalling
+RCTs of each
Can鈥檛 compare between drugs #efficacy
馃し
#ACR2026 @RheumNow @ACRheum
#LB22
#1861 shows #Iana effects
#dry #Rx landscape
Which to choose in future?
#Ianalumab
#dazodalibep
DIff #MOA
#CD40L
#CD20 deleted+ altered B cell
Signalling
+RCTs of each
Can鈥檛 compare between drugs #efficacy
馃し
#ACR2026 @RheumNow @ACRheum
#LB22
#1861 shows #Iana effects
#Efgartigimod
#RCT in #inflammatory #myositis
Combined efficacy of #dermatomyositis
#IMNM
All primary combined and component Endpts met
Subsets favored #efgartigimod in both #DM & #IMNM
59% infection vs 48% PBO
SIE low
CK 鈽戯笍
#LB24 @ACRheum #ACR26 @RheumNow
#RCT in #inflammatory #myositis
Combined efficacy of #dermatomyositis
#IMNM
All primary combined and component Endpts met
Subsets favored #efgartigimod in both #DM & #IMNM
59% infection vs 48% PBO
SIE low
CK 鈽戯笍
#LB24 @ACRheum #ACR26 @RheumNow
Primary SRI-4 in active #SLE met
W TLR7/8
#AFIMETORAN
Wow! RCT is 鈽戯笍
Less infections and great high bar outcomes
#ACRbest
#LB23 @RheumNow @ACRheum
W TLR7/8
#AFIMETORAN
Wow! RCT is 鈽戯笍
Less infections and great high bar outcomes
#ACRbest
#LB23 @RheumNow @ACRheum
NEW #MOA in #SLE
TLR7/8
#Afimetoran
Drives Interferon T1 TLR7
Changes organ damage TLR8
1 or more background #lupus #Rx
mandated #prednisone taper
Aim <7.5mg/d #GCs
Mean #SLEDAI 8, CLASI 7-8
Mean pred 9.5-10.5
85%HCQ
#ACR26 @RheumNow @ACRheum
#LB24View quoted post on X