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Jay Bradner, M.D.

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@jaybradner

Physician-scientist making medicines with friends, memories with family. EVP R&D at Amgen
Thousand Oaks, CA linkedin.com/in/jaybradner Joined September 2011
923 Following 24K Followers 2.6K Posts

Latest posts 5

Jay Bradner, M.D. Verified account @jaybradner
Jon Clardy was a brilliant scholar and a wonderful man, beloved uniformly in chemistry and chemical biology from Boston to Brazil. My sincerest condolences to those who were lucky to know him well, as mentees and close friends. RIP, Jon, just cannot believe you are gone.
Michael Fischbach Verified account @mfgrp Nov 2
Jon Clardy: 1943-2026
One of the most impactful, creative, and (quietly) irreverent practitioners of chemical biology. Transformed how we think about nature's chemicals: their structures, their role in biology. Loved him -- he had tremendous influence on my thinking.
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Jay Bradner, M.D. Verified account @jaybradner
Very sad to lose Mike Ditka. He was one of my Father’s true heroes, and running into him at Nite N Gale’s restaurant in Highwood, IL, was as close as what we had growing up in suburban Chicago to meeting a celebrity. Having met a few more now, it was in fact much bigger. A giant presence, personality and commitment to our city. Rest easy, Coach.
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Jay Bradner, M.D. Verified account @jaybradner
Very compelling mechanistic rationale for targeting the Fanconi and NHEJ pathways in Ewing Sarcoma. Figure 7 is impressive wrt Indusilam activity in models (RBM39 degradation). If therapeutic index exists or can be engendered, could be interesting. Enjoyed this study thoroughly.
Dana-Farber News Verified account @DanaFarberNews Jul 21
New research from Alan D’Andrea, MD published in @MolecularCell reveals that Ewing Sarcoma has a profound DNA repair defect, making it a strong candidate for targeted therapy.

cell.com/molecular-cell…
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Jay Bradner, M.D. Verified account @jaybradner
All in the Simi Valley area and neighboring communities, please take note of this new Sandy Fire and wind patterns. Stay safe and take best care.
KTLA 5 Morning News @KTLAMorningNews May 18
#BREAKING:
Fire crews are currently battling a brush fire in Simi Valley. @LAflyingcameras overhead NOW.
Tune in to KTLA 5 or stream via the KTLA app 📲, KTLA+ 💻 or KTLA.com
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