James moon

@JccmoonMoon

Professor of Cardiology. Cardiac MRI. CEO Mycardium AI Ltd @MycardiumAI

mycardium.com Joined August 2014

240 Following 1.7K Followers 358 Posts

Latest posts 5

James moon @JccmoonMoon Jun 8, 2023

Congratulations to marianna and team: the discovery of spontaneous antibody mediated “autoimmunity” curing cardiac amyloidosis @NEJM Those images really are that order! Further support for Ab based therapy for amyloid @dr_m_fontana @RoyalFreeNHS #amyloidosis @SCMRorg #WhyCMR

Eric Topol Verified account @EricTopol Jun 7, 2023

That's pretty striking
Reversal of amyloidosis cardiomyopathy in 3 individuals who had developed anti-ATTR amyloid antibodies
nejm.org/doi/full/10.10… @NEJM @MariannaFonta11

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James moon @JccmoonMoon Mar 23, 2023

Fantastic work Becky. Completely unexpected result - 100% rate of perfusion defects in ApHCM: impossible that this is not significant for understanding/treating this under recognised disease. 2 chamber perfusion maps @UCL_ICS @UCLHresearch @BartsHospital @TheBHF

RebeccaHughes @DrRebeccaHughes Mar 23, 2023

Apical ischemia occurs in every single apical HCM patient, regardless of disease severity.

Read more here ⬇️
ahajournals.org/doi/10.1161/CI…

@JccmoonMoon @gabycaptur @mohiddinsam @LuisRLopesDr @UCL_ICS

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James moon @JccmoonMoon Feb 2, 2023

What mechanism heart injury during severe COVID? Comorbidity matched controls have frequent pre-existing scar (23%). Trop +ve COVID patients have double - but the MRI pattern is less myocarditis and more infarction and microinfarction. Circulation. shorturl.at/dwDMU

Injury pattern after troponin positive hospitalised COVID vs contemporary controls - COVID heart, a 25 centre prospective study.

James moon @JccmoonMoon Jun 14, 2022

Congratulations COVIDsortium team: 3rd Science paper. It's getting complicated. Your precise "exposome" - vaccines plus prior infections really matters - a mixed picture: no longer just "hybrid immunity", but now "Hybrid immune damping"!
@dr_manisty @ThomasTreibel @AineMcKnight

RosemaryBoyton @BoytonRosemary Jun 14, 2022

Immune imprinting following first wave infection with ancestral SAR-CoV-2 ablates immune boosting following Omicron infection despite 3-dose vaccination

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James moon @JccmoonMoon Jun 7, 2022

Congratulations Becky and team. Great coverage of important interesting results @NHSBartsHealth @UCL_ICS @TheBHF @AnishBhuva @torlascoc @AndrewJMDSilva @parry_williams

RebeccaHughes @DrRebeccaHughes Jun 7, 2022

I’m delighted that my work exploring sex differences in aortic stiffness in masters athletes, which I presented at the #BCS100 has been reported in @thetimes @Telegraph @DailyMailUK @JccmoonMoon @SSharmacardio @gabycaptur @dr_manisty @UCL_ICS @TheBHF @CryCardiac
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