Jean-Ju Chung

@JeanJuChung

Ion Channels & Reproductive Physiology Lab @ Yale, CatSper, Sperm, Mammalian Fertilization

jeanjuchunglab.org Joined April 2021

161 Following 300 Followers 140 Posts

Latest posts 5

CATSPERε extracellular domains are essential for sperm calcium channel assembly and activity modulation | Science Advances science.org/doi/10.1126/sc…
Finally out after a long lag since its preprint. Kudos to Jae Yeon for tackling tough protein purification during revision!

www.science.org CATSPERε extracellular domains are essential for sperm calcium channel assembly and activity... CATSPERε ECDs are essential for CatSper canopy and holo-complex assembly and regulate channel activity during sperm capacitation.

Jean-Ju Chung @JeanJuChung Feb 3, 2025

A late posting for a preprint from the lab after long silence biorxiv.org/content/10.110…
In this study, we delineate CatSper’s assembly order and a binding surface for activity modulation, offering CatSper canopy as potential target for fertility control

www.biorxiv.org CATSPERε extracellular domains are essential for sperm calcium channel assembly and activity... The sperm flagellar-specific CatSper Ca2+ channel is a multiprotein complex critical for successful fertilization. The four ancillary subunits, CATSPERβ, γ, δ, and ε, form a unique canopy structure...

Jean-Ju Chung @JeanJuChung Oct 19, 2023

Yale PhD admission info session (TMMPP)!

Jean-Ju Chung @JeanJuChung Sep 24, 2023

A postdoc position available in my lab at Yale School of Medicine. Background in ion channels and membrane receptors and experience with mouse work is preferred. Highly motivated and independent candidates with an inquisitive nature and a quantitative mind are encouraged to apply

Jean-Ju Chung @JeanJuChung Sep 21, 2023

A CUG-initiated CATSPERθ functions in the CatSper channel assembly and serves as a checkpoint for flagellar trafficking | PNAS pnas.org/doi/abs/10.107… It is now official. A great collaboration with @Percud and Ikawa labs!