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Joseph DeSimone

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@Joseph_DeSimone

Prof @Stanford; Founder: @PinPrint, @Carbon, @FocalMedical, @Solid_Battery, @Liquidia_Inc, BVS; Trustee: @UrsinusCollege (Chair, BOT), @NatGeo | La vita è bella
desimonegroup.stanford.edu Joined August 2011
2.4K Following 9.3K Followers 11K Posts

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Joseph DeSimone Verified account @Joseph_DeSimone
As a longtime @Eagles season ticket holder, I’m deeply disappointed and troubled by the news about @JalenHurts . Players’ health and safety must always come before winning games. Eagles fans deserve transparency about how these medical decisions were made. Accountability matters. #FlyEaglesFly
World News Tonight Verified account @ABCWorldNews Oct 19
Jalen Hurts, the Philadelphia Eagles star quarterback, is out for the rest of the season after doctors discovered a blood clot in his leg and clots in both his lungs. The former Super Bowl MVP is expected to make a full recovery. @RhiannonAlly has details. abcworldnewstonight.visitlink.me/qIGMAZ
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Joseph DeSimone Verified account @Joseph_DeSimone
@jimgoetz — completely agree. @bgurley’s framing is powerful. After Challenger, Fukushima, Katrina, the 737 MAX crashes, Surfside and other catastrophes, we investigated relentlessly—not simply to assign blame, but to understand what happened, learn from it, and make the world safer.

COVID demands at least that same standard. And North Carolina has a particular responsibility here. @UNC and @DukeU should be complete open books and help this investigation to the fullest extent possible. No hiding behind lawyers, institutional interests, carefully parsed definitions or procedural arguments. Society needs the scientific and academic community to lead in the search for answers—not impede it.

As Gurley quotes: “We can easily forgive a child who is afraid of the dark; the real tragedy of life is when men are afraid of the light.”

The urgency is actually greater today than it was in 2020. The convergence of AI, synthetic biology and increasingly powerful genome engineering is going to give scientists capabilities we could barely imagine a decade ago. Another pandemic is possible, and the consequences of biological research going awry—accidentally or deliberately—could become much greater.

That is why understanding COVID’s origins matters so much. Not to relitigate the past, but to prepare for the future. We need to understand what happened, what we got right, what we got wrong, and what safeguards are warranted as AI and biology converge.

Carolina in particular should lead here, not hide. Universities exist to pursue truth, especially when the truth is uncomfortable. This is a moment for academic leadership—and for stepping into the light.
jim goetz Verified account @jimgoetz Sep 20
Agreed. A timely reminder, and a spectacular call to action. @Joseph_DeSimone @UNC @DukeU
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Joseph DeSimone Verified account @Joseph_DeSimone
Big moment today!

How many of you have seen the recent reports—nanoparticle mRNA vaccines starting to show real signals in pancreatic cancer?

That’s the moment we’re in.

And today, Amy Latursky successfully defended her PhD at @Stanford right at that frontier.

Her work tackles the next limitation head-on. Today’s systems are powerful—but limited. Amy built a platform that decouples the nanoparticle, the RNA payload, and the targeting strategy—making RNA delivery modular, customizable, and programmable.

Pre-make the scaffold. Load on demand. Target with precision. That’s where this field is going.

Proud of you, Amy (except for how far you sent the champagne cork!). Onward!