Jonathan Weissman's Lab

@JswLab

Jonathan S. Weissman's lab at the @WhiteheadInst/@MIT. Account run by lab members.

Cambridge, MA weissman.wi.mit.edu Joined October 2019

3.5K Following 11K Followers 209 Posts

Latest posts 5

New preprint on generative modeling for mouse development! Rather than single cell trajectories, we set out to model embryos as trees.

Led by @gokl_g, @njwfish, @WilliamNColgan, w/ Philippe Rigollet, @stats_stephen, Zack Smith, @marinkazitnik, @lukekoblan and a wonderful team

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Jonathan Weissman's Lab @JswLab 6d

Excited to share Pycea, a new Python toolkit for lineage analysis and visualization developed by @WilliamNColgan!

Pycea brings lineage trees into the scverse ecosystem, enabling seamless analysis of lineage, gene expression, and spatial data.

biorxiv.org/content/10.648…

Jonathan Weissman's Lab @JswLab Oct 8

Thrilled to share that our work reconstructing a cell fate map of the mouse embryo is out now in @CellCellPress! doi.org/10.1016/j.cell…

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Jonathan Weissman's Lab @JswLab Oct 2

A discovery of a novel resilience factor from a genome-scale ORF screen. Led by @Y_Ryan_Lu in the lab - five+ years in the making.

Yuancheng Ryan Lu Verified account @Y_Ryan_Lu Oct 2

1/ Excited to share our new preprint from a joint collaboration between @JswLab + @Bruce_Ksander!

Aging is marked by a progressive loss of resilience to stress. Can we systematically search the human ORFome for genes that make vulnerable cells more resilient?

Performing such a genome-scale ORF screen led us to NKX2-5—a heart transcription factor we engineered to restore vision, and improve health in aged mice.

A breakdown🧵
🔗 doi.org/10.64898/2026.…
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Jonathan Weissman's Lab @JswLab Sep 9

We’re hiring a Technical Assistant I/II in the Weissman Lab @WhiteheadInst to work on in vivo functional genomics with multimodal readouts.

Our technicians have had incredible success going on to PhD & MD/PhD programs. Apply or send great candidates our way!