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Katherine Isoardi

@KIsoardi

Emergency Physician & Clinical Toxicologist. Medical Director Queensland PIC and PA hospital Tox Unit. Tox Queen of the North (but in the South)
Brisbane, Queensland Joined November 2012
120 Following 225 Followers 179 Posts

Latest posts 5

Katherine Isoardi @KIsoardi
What is the best approach for parenteral sedation to manage severe acute behavioral disturbance in the emergency department?
Here is our opinion ... @GeoffIsbister @bobhoffmd
Free reprints here tandfonline.com/doi/full/10.10…
www.tandfonline.com What is the best approach for parenteral sedation to manage severe acute behavioral disturbance in... Patients with severe acute behavioural disturbance commonly present to the emergency department. Differing expert opinion dominates treatment strategies. We describe an evidence-based approach to p...
Katherine Isoardi @KIsoardi
Do you ask about dander allergy before giving antivenom?? I do now… can read why here @geoff_isbister @angelachiewa

tandfonline.com/eprint/FFZUDFN…
www.tandfonline.com Life-threatening anaphylaxis following antivenom administration in two patients with horse dander... Antivenom is used to treat systemic envenomation and is immunoglobulin G raised from animals, mainly horses, inoculated by venom.We report two cases of life-threatening anaphylaxis following the ad...
Katherine Isoardi @KIsoardi
Serotonin toxicity was common in our series of lamotrigine overdose. Not related to dose/concentration but rather whether there was another serotonergic agent present. @angelachiewa Free copies here tandfonline.com/eprint/DKQXXGK…
www.tandfonline.com Clinical effects of acute lamotrigine overdose (ATOM-10) Lamotrigine overdose is not typically associated with severe toxicity. However, both severe toxicity and serotonin toxicity is occasionally reported following large ingestions. We aimed to investig...
Katherine Isoardi @KIsoardi
Free reprints for ATOM - 9, our study on propranolol overdose available here @geoff_isbister @angelachiewa tandfonline.com/doi/full/10.10…
www.tandfonline.com A prospective study of acute propranolol overdose defining dose thresholds of severe toxicity (ATOM... Propranolol is a beta-adrenoceptor blocking drug with sodium channel-blocking properties that can cause life-threatening toxicity in overdose. Limited research defines dose thresholds of toxicity. ...
Katherine Isoardi @KIsoardi
Dihydropyridines are different. Don’t treat all CCB overdose the same way. ⁦@geoff_isbister⁩ Calcium channel blocker overdose: Not all the same toxicity - Isbister - British Journal of Clinical Pharmacology - Wiley Online Library bpspubs.onlinelibrary.wiley.com/doi/full/10.11…
bpspubs.onlinelibrary.wiley.com BPS Publications Aims Calcium channel blocker (CCB) overdose remains an important poisoning, with increasing availability of dihydropyridines. We aimed to compare the severity and treatment of CCB overdoses. Method...