Konstantopoulos Lab

@KKLabJHU

Cancer Metastasis | Cell Motility | Bioengineering @ JHU

Johns Hopkins University kostaslab.johnshopkins.edu Joined October 2019

272 Following 839 Followers 204 Posts

Latest posts 5

Proud of this work led by the @JudeM_Phillip lab, now in @NatureComms! Elevated fluid viscosity restores young-like surveillance behaviors in aged T cells. New insights at the intersection of mechanobiology and immune aging! Congratulations to Yoseph, @alice_amitrano and the team

Konstantopoulos Lab @KKLabJHU Oct 15

The Konstantopoulos Lab is heading to Orlando for #BMES2026! 🧬

We're excited to share our latest findings on cell mechanobiology and how microenvironmental cues shape cellular behavior. Looking forward to presenting our research and engaging in new scientific discussions!

Konstantopoulos Lab @KKLabJHU May 11

So proud of our lab alumnus, @KaustavBera11 (PhD ’22), on joining @PurdueChemE as an Assistant Professor! Excited to see him launch his lab and continue advancing the frontiers of mechanobiology, biomaterials and tissue engineering. Wishing him every success in this new chapter!

Konstantopoulos Lab @KKLabJHU May 7

Congratulations to our PhD student @NitishSriv24401 on winning first place for poster presentation at the @INBT_JHU 19th Nano-Bio Symposium! He presented work on how our microfluidic devices can be used to predict GBM patient survival and advance precision medicine approaches.

Konstantopoulos Lab @KKLabJHU Apr 2

Pleased to share our collaborative work with the Kontrogianni group, now out in Advanced Science @AdvPortfolio. Led by Matthew & @Anindya_SenJHU , we show how delivery of PH domains suppress PI3K/Akt signaling and breast cancer metastasis. Read more:
advanced.onlinelibrary.wiley.com/doi/10.1002/ad… [1/4]

advanced.onlinelibrary.wiley.com Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini-o...