King Lab

Excited to share our latest @biorxivpreprint, led by Dr. Chelsea Fries @assemblingfries 🥳

Here, we establish multistate interface design as a strategy for engineering protein assemblies that break symmetry and switch between distinct geometries.

bit.ly/47ZqHNK

🚨 pre-print alert 🚨

Glycosylation has remained outside the reach of biomolecular design, but with new all-atom methods we are now able to control the types of glycans displayed on our de novo proteins.

In our newest @biorxivpreprint, we present multiple structurally-encoded oligomannose-type glycoproteins, establishing glycans as a designable parameter!

bit.ly/4s2qK4M

🚨 new paper alert 🚨

Here we apply our protein nanoparticle vaccine platform toward a bacterial indication: uropathogenic E. coli, the primary causative agent of UTIs:

bit.ly/4waDqaM

Last week, Grace Hendricks successfully defended her dissertation and earned her PhD!

🚨 new paper alert 🚨

Here we demonstrate increased anti-RBS neutralizing responses elicited by stabilized influenza H5 immunogens:

bit.ly/4u8UxJl