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Kitching Laboratory

@KitchingLab

Led by Richard Kitching, focused on #immunology of #vasculitis #nephritis.
Chair @ANZVASC, Co-convenor 2026 Int Vasculitis Wkshop. vasculitis-melbourne2026.com
Monash Univ/Monash Health monash.edu/medicine/scs/m… Joined December 2017
217 Following 921 Followers 531 Posts

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Kitching Laboratory @KitchingLab
Time is critical in AAV: dampening kidney inflammation prevents damage
Why not target effector T cells - leave other T cells alone?
Our paper in @NDTSocial defines IL-7Ra as a target
doi.org/10.1093/ndt/gf…
Anti-IL-7Ra Abs are in Phase 2 trials - alopecia @Q32Bio ?an AAV therapy
academic.oup.com Neutralizing the IL-7Rα limits injury in experimental ANCA-associated glomerulonephritis ABSTRACTBackground and hypothesis. Increased T-cell interkeukin (IL)-7Rα signalling is associated with a poorer prognosis in anti-neutrophil cytoplasmic an
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Kitching Laboratory @KitchingLab
Don't miss Prof Mackay's plenary. She a world-leading scientist and fantastic communicator!
PS for all you "BVAS people," her PhD was at Birmingham University on T cells and EBV
ANZ Vasculitis Society, '26 Vasculitis Wkshop host @anzvasc Nov 18, 2025
We’re excited to welcome Professor Laura Mackay to the International Vasculitis Workshop 2026!

As Professor and Immunology Theme Lead at the Peter Doherty Institute, she brings outstanding expertise to the 2026 program.

Register: vasculitis-melbourne2026.com/registration/
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Kitching Laboratory @KitchingLab
Early bird rego just might stay open over the weekend, Australian time. It's not too late to join over 600 others registered at the cheap rate!
ANZ Vasculitis Society, '26 Vasculitis Wkshop host @anzvasc Nov 12, 2025
Early Bird registration for the 22nd International Vasculitis Workshop closes in just 48 hours! This is your last opportunity to save on your ticket - don’t miss out! Register by 14 November 2025 at vasculitis-melbourne2026.com/registration/
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Kitching Laboratory @KitchingLab
Last chance everyone!
Submit your abstract and join the over 55 invited international speakers at the Workshop #vasculitismelbourne2026
Case reports and case series are welcome
And remember the new Young Invstigator Award Session.
See you in 2026!
ANZ Vasculitis Society, '26 Vasculitis Wkshop host @anzvasc Sep 18, 2025
We’re giving you more time to share your work at the upcoming International Vasculitis Workshop. The new deadline to submit your abstract is 29 September 2025!
Don't miss your opportunity, submit today at vasculitis-melbourne2026.com/call-for-abstr…
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Kitching Laboratory @KitchingLab
IL-7Ra signalling in AAV links to relapse/resistance
Our recent paper
🔹defined activated & exhausted T cells in experimental AAV kidneys
🔹neutralised IL-7Ra - a non-depleting mAb - to limit ANCA-associated GN
Similar mAbs are in Phase 2 clinical trials
academic.oup.com/ndt/article-ab…
academic.oup.com Neutralizing the IL-7Rα limits injury in experimental ANCA-associated glomerulonephritis ABSTRACTBackground and hypothesis. Increased T-cell interkeukin (IL)-7Rα signalling is associated with a poorer prognosis in anti-neutrophil cytoplasmic an