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Woolner Lab

@LabWoolner

Sarah Woolner's lab at the University of Manchester, UK. We investigate mechanical regulation of cell division in developing tissues.
University of Manchester woolnerlab.wordpress.com Joined February 2019
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Woolner Lab @LabWoolner
Check out our new preprint on bioRxiv. We show that NuMA localisation is sensitive to tissue stretch and acts to fine-tune division orientation.

Mitotic spindle orientation and dynamics are fine-tuned by anisotropic tissue stretch via NuMA localisation biorxiv.org/content/10.110…
www.biorxiv.org Mitotic spindle orientation and dynamics are fine-tuned by anisotropic tissue stretch via NuMA... Significance Mechanical forces regulate cell division orientation, which is important for cell fate and tissue shaping. Cells generally orient divisions along their long axis of interphase shape and...
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