Nice one table summary by @brian_rini putting today’s LITESPARK-011 results (presented just now @GU26) in context. @Uromigos @DukeCancer
Combination therapy is emerging as a standard in refractory RCC. Combos increase tumor shrinkage endpoints. TKI provides early disease control. CRs are possible but is cure? Toxicity consideration is critical in this setting. Biomarkers to guide choice of drug(s) are neededView quoted post on X