Max Ruwolt

Newest publication from our lab 🚨 @BorisBogdanow used some of our datasets to show the terrific benefits of fused target-decoy searches and context-sensitive FDR filtering for increasing crosslink identification sensitivity and reliability. (1/2) embopress.org/doi/full/10.10…

Our DSSO xlinked PPI benchmarking dataset (PXD042173) and Scout (github.com/diogobor/Scout) are finally published (nature.com/articles/s4159…)! Both Scout and the PPI dataset will grow. We and the whole XL community are working hard on refining XL search and FDR estimation.

#PhDone Last week I defended my PhD thesis.👨🏼‍🎓 Many thanks for the nice celebration and the coolest gifts. 🤩 But most importantly: thanks to all the friends and colleagues for creating wonderful memories over the past 3.5 years, both inside and outside the lab.

@theliulab @Julia_Rta at #ASMS2024. We're 3 days in and had 3 poster presentations with lots of discussions on XL-MS. It was great to meet many old and new friends. But is it just me or is the XL-MS community a little under-represented?

Pyrophosphrylation is an interesting but understudied PTM. In the most recent paper from Fiedler lab at @LeibnizFMP, @JeremyAMMorgan made the first (but large) step towards pyrophosphoproteomics. Still, we're constantly optimizing the workflow.

nature.com/articles/s4158…