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Happy Friday all! My work developing a model of MATR3 is now available online @iScience_CP, check it out! @JackrelLab cell.com/iscience/fullt…
Macy Sprunger
@MacySprunger
PhD candidate in @JackrelLab at WUSTL. Interests: biochemistry, disordered proteins, biomolecular condensates, and quilting
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Just two weeks away from defending my Ph.D. in @JackrelLab 🎈Send me a message if you are interested in the zoom details!
My lab mates have been up to some cool work on bacterial biofilm components! Congrats team!
Thrilled to share the lab’s latest work where we dive into the world of bacterial biofilms! 🧫 Here we developed a yeast model to study the aggregation and toxicity of the amyloidogenic PSM proteins from S. aureus.View quoted post on X
Exciting new MATR3 study out from @BarmadaLab! pnas.org/doi/10.1073/pn…
www.pnas.org Neuronal activity regulates Matrin 3 abundance and function in a calcium-dependent manner through... RNA-binding protein (RBP) dysfunction is a fundamental hallmark of amyotrophic lateral sclerosis (ALS) and related neuromuscular disorders. Abnorma... Had fun getting creative to make a lab logo!
We have a lab logo now! The line represents the protein folding energy landscape of an IDP with an amyloid fold. We love IDPs and altering their conformations with chaperones and disaggregases!View quoted post on X