Our in vivo multiplexing scaled so far we had to build a design framework to keep up. Introducing mBER-2, the latest iteration of our scaled protein binder design platform, updated from experimental feedback from millions of measured designs.
Manifold Bio
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Organism-scale intelligence, designed in vivo
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Excited to be an early partner in Anthropic's Life Sciences Verification Program
Today we’re opening applications for the Life Sciences Verification Program.View quoted post on X
Through the LSVP, life science professionals can use our models—including, for the first time, Mythos—with a new set of safeguards designed to enable the full range of biology-related work. We designed these new safeguards to provide a better experience for biologists and more protection from risk of misuse.
The program is launching in beta for teams of all kinds—from academic labs to startups, pharma companies, and more. We will continue to improve the program and expand access to individual Pro and Max plans over time.
Learn more about these access grants and apply: anthropic.com/news/life-scie…
Manifold Bio is heading to @RosettaCommons Summer RosettaCon 2026 next week.
Erik Swanson and Mike Nichols will present the EpiTome, our proteome-scale effort to design binders to every addressable epitope on every human cell-surface receptor.
We’ll talk about highlights from our latest million-scale de novo antibody design and validation campaigns. Our data now exceeds the number of antibody-antigen interaction complexes in the PDB by more than an order of magnitude.
We're pushing the boundary of data scale in protein design, closing the loop between design and validation at a pace and density the field has never seen. DM to connect with Erik or Mike.
📅 August 6, 2026, 1:30pm PT
📍 Seattle, WA
Erik Swanson and Mike Nichols will present the EpiTome, our proteome-scale effort to design binders to every addressable epitope on every human cell-surface receptor.
We’ll talk about highlights from our latest million-scale de novo antibody design and validation campaigns. Our data now exceeds the number of antibody-antigen interaction complexes in the PDB by more than an order of magnitude.
We're pushing the boundary of data scale in protein design, closing the loop between design and validation at a pace and density the field has never seen. DM to connect with Erik or Mike.
📅 August 6, 2026, 1:30pm PT
📍 Seattle, WA
Our CSO, Kimberly Scearce-Levie, is headed to London! Come listen to her talk at the AAIC on one of the central challenges in CNS drug development: getting therapeutics to the brain.
Getting the right drug to the right tissue is one of the hardest problems in medicine. @ManifoldBio is presenting data on how we're solving it at the Barriers of the CNS Gordon Research Conference next week.
Supriya Ravichandran will present our poster on ultra high-throughput in vivo screening for CNS shuttle discovery. Screening hundreds of thousands of in silico-designed molecules simultaneously in vivo, we identify novel receptor portals and tissue-targeting shuttles with differentiated biodistribution profiles.
Massively multiplexed in vivo screening is how we turn drug localization from a bottleneck into a solvable design problem, with the same engine extending across tissues and indications.
Attending? DM us to connect with Supriya or Marshall Case. 👋
📅 June 14-19, 2026 | New London, NH
📍 grc.org/barriers-of-th…
Supriya Ravichandran will present our poster on ultra high-throughput in vivo screening for CNS shuttle discovery. Screening hundreds of thousands of in silico-designed molecules simultaneously in vivo, we identify novel receptor portals and tissue-targeting shuttles with differentiated biodistribution profiles.
Massively multiplexed in vivo screening is how we turn drug localization from a bottleneck into a solvable design problem, with the same engine extending across tissues and indications.
Attending? DM us to connect with Supriya or Marshall Case. 👋
📅 June 14-19, 2026 | New London, NH
📍 grc.org/barriers-of-th…
