I’m super excited to share that I received an @ERC_Research Starting Grant!! The DECODE-PMD project will boost research in my new lab @CRGenomica to unravel how nascent proteins can trigger degradation of their own mRNA during translation.
Markus Höpfler
@MarkusHopfler
Group leader @CRGenomica | protein synthesis | RNA decay | tubulin homeostasis
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Apply until 12th of January for the @CRGenomica international PhD programme! There will be 2 positions in my group with a focus on novel mechanisms of mRNA decay in the context of microtubule regulation. Please RT! crg.eu/en/content/tra…
Finally out! We identify the first regulatory step in the tubulin autoregulation pathway: TTC5 is sequestered by free αβ-tubulins to prevent it from ribosome binding. Thanks for a great collaboration with @Ivana_Gasic and Zhewang Lin! nature.com/articles/s4146…
www.nature.com Soluble αβ-tubulins reversibly sequester TTC5 to regulate tubulin mRNA decay Nature Communications - When tubulin proteins are present in excess, their encoding mRNAs are selectively degraded in a process initiated by the protein TTC5. Here, the authors show that tubulins... Looking forward to being @CambridgeRNA club again!
Ready for this week's RNA Club? This Thursday we'll be hosting @MarkusHopfler and @MuratSunbul_Lab at the @CamBiochem (Sanger Building) for some interesting talks! Hope to see you there! 🍻🍕🧬Thanks to @RNASociety @lexogen @2BScientific @CambridgeBiosciView quoted post on X
The CRG has an outstanding international PhD programme, do apply!!!
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