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Meanwell Lab

@Meanwell_Lab

Organic synthesis lab @uAlberta working on synthetic methods, total synthesis, medicinal chemistry, and materials science
University of Alberta meanwellresearchlab.com Joined August 2022
249 Following 1.4K Followers 53 Posts

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Meanwell Lab @Meanwell_Lab
Want a detailed step-by-step guide of our nucleoside analogue (NA) synthesis platform? Check out our Nature Protocol (nature.com/articles/s4159…) where we discuss its use on 85g scale and its expansion to other modifications/nucleobases. @Thirupathichem
www.nature.com Preparation of C4′-modified nucleoside analogs Nature Protocols - Nucleoside analogs are used in the treatment of diseases and as components of oligonucleotide therapeutics. This protocol describes a generalized, five-stage synthesis of...