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Mercedes Guerrero

@MerGuMu

PhD student at Josep Carreras Leukaemia Research Institute @CarrerasIJC @Menendez_Lab
Bioinformatician 💻🔬
T cells & CAR T cells 🧪🧫
Barcelona Joined May 2014
780 Following 305 Followers 204 Posts

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Mercedes Guerrero @MerGuMu
Thrilled to share that the first project of my PhD has been published in @CellRepMed!
Couldn’t be happier or more grateful to @rill_aina, @eli_mereu, @clarabueno_74 & @Menendez_Lab.
Go take a look!
cell.com/cell-reports-m…
#CAR_Tcell #Immunotherapy
www.cell.com Integrative single-cell multi-omics of CD19-CARpos and CARneg T cells suggest drivers of immunoth... Guerrero-Murillo and Rill-Hinarejos et al. demonstrate that phenotypic, clonal, and functional heterogeneity of CAR-T cells affect outcomes in B-ALL patients treated with CD19CAR-T therapy. Differe...
🚨Researchers from the @Menendez_Lab and @eli_mereu Lab, @MerGuMu @trincadojl @rill_aina describe at @CellRepMed the molecular features making a CAR-T cells infusion successful 💪

Read the news piece at 👇
carrerasresearch.org/en/news/intrin…

Results show objective features in the infusion product may predict future therapeutic success, advocating for a more precise quality control.
Also, characteristics of the CAR-T expansion within the patient are related to efficacy and could be used as early warning.

Thanks to funders 🫶 @contracancerINV @FundlaCaixa @unoentrecienmil @fcarreras
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