Molecular Metabolism

Check out our 𝗡𝗼𝘃𝗲𝗺𝗯𝗲𝗿 𝗜𝘀𝘀𝘂𝗲!

💉 Cover Story: Exploring the direct effects of #semaglutide versus equivalent calorie restriction on the reproductive systems of male and female rats - sciencedirect.com/science/articl…

💉 Browse the full issue: molecularmetabolism.com

🧬 What role does β-klotho play in liver metabolism?

New research reveals that hepatic β-klotho deficiency disrupts lipid homeostasis, reducing VLDL secretion and promoting fat accumulation in the liver.

🏛️@umcg @researchumcg
🔗sciencedirect.com/science/articl…

How do pancreatic islets release GABA? 🔬

A new biosensor cell array reveals pulsatile #GABA secretion linked to calcium oscillations – but not directly to insulin release.

🏛️@ufdiabetes @UCIrvine
🔗sciencedirect.com/science/articl…

The genetics of #Type2Diabetes goes beyond single nucleotide variants!

A new review explores how structural variants, mobile elements, tandem repeats, and mitochondrial DNA changes contribute to diabetes risk and metabolic dysfunction.

🏛️@incliva_iis
🔗sciencedirect.com/science/articl…

Could targeting cancer metabolism offer a new strategy against #TripleNegativeBreastCancer?

Combining #Carnosine with ASAH1 inhibition enhances antitumor effects by disrupting mitochondrial function and promoting cancer cell death.

🏛️@UABNews
🔗sciencedirect.com/science/articl…