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🚨Preprint alert!
STRAIGHT-IN Dual allows the generation of homogenous genetically-modified hiPSCs
▪️ Done in 1 week with ~100% efficiency
▪️ Markerless and near-scarless approach performed in >10days in a single-well
▪️ Carrying not one but two (single-copy) payloads
See🧵below!
STRAIGHT-IN Dual allows the generation of homogenous genetically-modified hiPSCs
▪️ Done in 1 week with ~100% efficiency
▪️ Markerless and near-scarless approach performed in >10days in a single-well
▪️ Carrying not one but two (single-copy) payloads
See🧵below!
So you want to engineer your hiPSCs, but targeting DNA payloads requires multiple slow, inefficient steps for each construct. What if we could accomplish multi-site integration seamlessly?
🚨Introducing STRAIGHT-IN Dual! 🧵 (1/n)
Link: biorxiv.org/content/10.110…View quoted post on X
