Mustafa Mir-@mirlab.bsky.social

@MustafaMir16

We study transcription and nuclear organization using cutting edge microscopy. Asst. Prof. @CHOP_CCGM @PennCDB @HHMINEWS Freeman Hrabowski Scholar

Philadelphia, PA mir-lab.com Joined February 2017

1K Following 1.7K Followers 692 Posts

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Mustafa Mir-@mirlab.bsky.social @MustafaMir16 Jun 12, 2023

Check out this video about life in our lab made by the very talented @CHOP_Research Creative Services team as part of their "lab life" series (research.chop.edu/categories/lab…)
youtube.com/watch?v=_A6Go_…

Mustafa Mir-@mirlab.bsky.social @MustafaMir16 Jan 17, 2025

Big congratulations to our MD/PHD student
@alexadigun3
on receiving a F31 award from NIGMS to "Illuminate the Molecular Mechanisms of Replication and Transcription Coordination" during zygotic genome activation and support her training.

Mustafa Mir-@mirlab.bsky.social @MustafaMir16 Oct 31, 2024

We had some fun with photo-physics this Halloween. See if you can figure out some of our (very) interpretative demonstrations of (FRET, photoconversion, &, localization microscopy). Happy Halloween!🤓🎃

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Mustafa Mir-@mirlab.bsky.social @MustafaMir16 Oct 21, 2024

Thanks to all in the community who gave constructive feedback. We have updated our pre-print including new imaging in additional mutants & genomics analysis. Open science and community peer review FTW in helping us strengthen our findings: biorxiv.org/content/10.110…

www.biorxiv.org A fine kinetic balance of interactions directs transcription factor hubs to genes Eukaryotic gene regulation relies on the binding of sequence-specific transcription factors (TFs). TFs bind chromatin transiently yet occupy their target sites by forming high-local concentration...

Mustafa Mir-@mirlab.bsky.social @MustafaMir16 Apr 17, 2024

1/n) Excited to share our new preprint: Using high-res live embryo imaging we show that transcription factor hubs are localized to new genes when specific DNA binding is perturbed. Hub interaction kinetics at these new sites determine factor occupancy: biorxiv.org/content/10.110…

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Mustafa Mir-@mirlab.bsky.social @MustafaMir16 Sep 17, 2024

Congratulations to S Fallacaro @littlescholar_ in the lab for receiving an honorable mention in the @NikonSmallWorld In Motion competition for their lovely compilation video of zooming into a fruit fly embryo: nikonsmallworld.com/galleries/2024…

www.nikonsmallworld.com Three views of a fruit fly (Drosophila melanogaster) | 2024 Small World in Motion Competition Samantha Fallacaro - Three views of a fruit fly (Drosophila melanogaster): adult, embryo, and histones tagged with GFP marking nuclei